Asset information for asset ID #3713751
Asset Basics:
3713751
86fb046b2b355eeec8c8b42045311fc8
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71kB
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350px
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27,416
Asset Origins:
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1 | 5-HT1A receptor agonists decrease blood pressure and heart rate via a central mechanism, by inducing peripheral vasodilation, and by stimulating the vagus nerve.[6] These effects are the result of activation of 5-HT1A receptors within the rostral ventrolateral medulla.[6] The sympatholytic antihypertensive drug urapidil is an α1-adrenergic receptor antagonist and α2-adrenergic receptor agonist, as well as 5-HT1A receptor agonist, and it has been demonstrated that the latter property contributes to its overall therapeutic effects.[7][8] Vasodilation of the blood vessels in the skin via central 5-HT1A activation increases heat dissipation from the organism out into the environment, causing a decrease in body temperature.[9][10] |
Asset usage:
title | views | votes | rating | creation | usage |
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?you won't see it til it's too late | 1,222 | 7 | (2.43) | 2011-01-11 | Background |